5 ml random urine in sterile urine container
Assure that lid is tightly closed to prevent leakage/test cancellation
Cotinine derives from nicotine. Once absorbed in the body, nicotine rapidly metabolizes to cotinine and cannot be detected in significant quantity in the urine. The half life of nicotine is short, about two hours. The half-life of cotinine is 10-37 hours which makes it a more reliable marker than nicotine. Cotinine, intrinsically being specific for tobacco, is the preferred marker for use of tobacco.