Test Directory

7224 Protein C Activity

Specimen Type
Specimen Stability
Reference Range
Citrated Plasma
14 Days, Frozen
-70° C: 1 year
70 - 180 % normal

Specimen Requirements

Specimen Type: Citrated Plasma
Container: 1 Light Blue Top Tube
Temperature: Frozen
Preferred Vol: 1.00 mL
Min Vol: 0.50 mL





Turn-Around Time



STRICT FROZEN. Separate Plasma and Freeze within 1 hour of collection.

Clinical Utility

The Protein C Activity done by a RVV type matrix coagulation assay is more sensitive to subclinical vitamin K deficiency, hepatic failure, coumadin and DIC. Some genetic mutations of protein C will be missed by the chromogenic assay which will be satisfactorily detected with the protein C clottable assay system. Alternatively, chromogenic assay may be more reliable to measure half-life and recovery of protein C concentrates.

CPT Codes


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