Test Directory

7258 Hemoglobinopathy Evaluation

Specimen Type
Specimen Stability
Reference Range
Whole Blood
6 Days, Refrigerated
14 Hours, Ambient
See Report

Specimen Requirements

Specimen Type: Whole Blood
Container: 1 Lavender Top Tube
Temperature: Refrigerated
Preferred Vol: 2.00 mL
Min Vol: 1.00 mL

Method

CELL CNT,HPLC

Schedule

Tuesday -Saturday

Turn-Around Time

Send-Out

Instructions/Notes

Clinical Utility

Used in the diagnosis of beta thalassemia sickling disorders, common structural hemoglobinapthies such as Hb S, C, E, D-Punjab, Lepore etc. It is also used in evaluating infants following abnormal newborn screening. Some forms of alpha-thalassemias are readily identified by HPLC e.g. when Hb Barts, Hb H, and/or Hb Constant Spring are observed. However, alpha-thalassemias resulting from only 1 or 2 alpha-globin gene deletion/nonfunction are not recognized in adults. Fortunately the majority (approximately 85-90%) of alpha thalassemia carriers have commonly encountered deletions which are identified in Alpha Thalassemia DNA Mutation Analysis. Rarer forms of alpha thalassemia (point mutations and small insertion/deletions) can be detected by Alpha-Globin Complete.

CPT Codes

83021, 85014, 85018, 85041

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