Specimen Type: Serum
Container: 1 Serum Separator Tube (SST)
Preferred Vol: 3.00 mL
Min Vol: 2.00 mL
Gas Chromatography/Mass Spectrometry (GC/MS)
Tuesday - Saturday
Frozen specimen is preferred.
Methylmalonic acid is a very sensitive indicator of Vitamin B12 deficiency at the tissue level. Mildly elevated levels (0.4-1.0 umol/L) are seen in patients with decreased renal function. Extremely high levels (>20 umol/L) are indicative of methylmalonic acidemia, an inborn error of metabolism disorder