Specimen Type: Serum
Container: 1 Serum Separator Tube (SST)
Preferred Vol: 1.00 mL
Min Vol: 0.50 mL
Enzyme Immunoassay (EIA); Latex Immunoassay (LIA)
Tuesday - Sunday
Autoantibodies to the protein components of the U1 variety of small nuclear ribonucleoproteins (U1 snRNP) are common in SLE-overlap syndromes (e.g., mixed connective tissue disease [MCTD]) and less so in SLE itself. High titers of autoantibody to U1 snRNP are a hallmark of MCTD.