Test Directory

7469 Aldolase

Specimen Type
Specimen Stability
Reference Range
Serum
5 Days, Refrigerated
14 Days, Frozen
See Report

Specimen Requirements

Specimen Type: Serum
Container: 1 Serum Separator Tube (SST)
Temperature: Refrigerated
Preferred Vol: 1.00 mL
Min Vol: 0.50 mL

Method

ENZYMATIC

Schedule

Monday - Saturday

Turn-Around Time

Send-Out

Instructions/Notes

Clinical Utility

This glycolytic enzyme is increased in a number of skeletal muscle conditions, including progressive Duchenne's muscular dystrophy (including carriers), dermatomyositis, polymyositis, limb-girdle dystrophy, myotonia dystrophy, and rhabdomyolysis. Normal values are seen in neurogenic atrophies. Elevated levels have been found in acute hepatitis, myocardial infarction, hemorrhagic pancreatitis, trichinosis, gangrene, prostatic tumors, carcinomas metastatic to the liver, granulocytic and megaloblastic anemias, delirium tremens, 60% to 80% of patients with acute psychoses and schizophrenia, and neoplasia. In recent years the assay of creatine kinase (CK) has replaced the assay of aldolase activity in serum, especially in muscular dystrophy. In acute viral hepatitis, increases tend to parallel ALT.

CPT Codes

82085

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