Test Directory

7511 Glutamic Acid Decarboxylase-65 Ab

Specimen Type
Specimen Stability
Reference Range
Serum
6 Months, Frozen
7 Days, Refrigerated
8 Hours, Ambient
< 1.1 U/mL

Specimen Requirements

Specimen Type: Serum
Container: 1 Serum Separator Tube (SST)
Temperature: Refrigerated
Preferred Vol: 1.00 mL
Min Vol: 0.20 mL

Method

Radiobinding Assay (RBA)

Schedule

Tuesday; Thursday; Saturday

Turn-Around Time

Send-Out

Instructions/Notes

Clinical Utility

Glutamic Acid Decarboxylase (GAD-65) Antibody is useful to diagnose insulin dependent diabetes mellitus (IDDM, Type I diabetes), to assess risk for development of IDDM, to predict onset of IDDM, and risk of development of related endocrine disorders, e.g., thyroiditis. Before clinical onset, Type I diabetes is characterized by lymphocytic infiltration of the islet cells, and by circulating autoantibodies against a variety of islet cell antigens, including GAD-65, IA-2 (a tyrosine phosphatase-like protein), and insulin autoantibody (IAA).

CPT Codes

83519

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